Biochemistry Publications

Recent Publications from Biochemistry

Developing antineoplastic agents that target peroxisomal enzymes: cytisine-linked isoflavonoids as inhibitors of hydroxysteroid 17-beta-dehydrogenase-4 (HSD17B4).
Organic & biomolecular chemistry
David S Watt
2017 Sep 4
Transient and permanent changes in DNA methylation patterns in inorganic arsenic-mediated epithelial-to-mesenchymal transition.
Toxicology and applied pharmacology
Yvonne N Fondufe-Mittendorf
2017 Sep 15
Fueling Platelets: Where Does the Glucose Come From?
Arteriosclerosis, thrombosis, and vascular biology
Sidney W. Whiteheart, Ph.D.
2017 Sep
The ins and outs of endocytic trafficking in platelet functions.
Current opinion in hematology
Sidney W. Whiteheart, Ph.D.
2017 Sep
Rad GTPase is essential for the regulation of bone density and bone marrow adipose tissue in mice.
Bone
Douglas A. Andres, Ph.D.
2017 Oct
Mutant IDH1 and seizures in patients with glioma.
Neurology
Craig Horbinski, M.D., Ph.D.
2017 May 9
Cancer-Associated IDH1 Promotes Growth and Resistance to Targeted Therapies in the Absence of Mutation.
Cell reports
Craig Horbinski, M.D., Ph.D.
2017 May 30
Layer-by-Layer-Assembled Laccase Enzyme on Stimuli-Responsive Membranes for Chloro-Organics Degradation.
ACS applied materials & interfaces
Anne-Frances Miller
2017 May 3
Incidence of CNS tumors in Appalachian children.
Journal of neuro-oncology
Craig Horbinski, M.D., Ph.D.
2017 May
Fluorinated N,N'-Diarylureas As Novel Therapeutic Agents Against Cancer Stem Cells.
Molecular cancer therapeutics
David S Watt
2017 May
Epigenomic reprogramming in inorganic arsenic-mediated gene expression patterns during carcinogenesis.
Reviews on environmental health
Yvonne N Fondufe-Mittendorf
2017 Mar 1
Editorial: Platelet Secretion.
Platelets
Sidney W. Whiteheart, Ph.D.
2017 Mar
The nuts and bolts of the platelet release reaction.
Platelets
Sidney W. Whiteheart, Ph.D.
2017 Mar
The activity of the serotonin receptor 2C is regulated by alternative splicing.
Human genetics
Stefan Stamm
2017 Jun 29
Genetic metabolic complementation establishes a requirement for GDP-fucose in <i>Leishmania</i>.
The Journal of biological chemistry
Salvatore J Turco
2017 Jun 23
Calcineurin/NFAT Signaling in Activated Astrocytes Drives Network Hyperexcitability in Aβ-Bearing Mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Michael Paul Murphy
2017 Jun 21
How an alloreactive T-cell receptor achieves peptide and MHC specificity.
Proceedings of the National Academy of Sciences of the United States of America
Craig William Vander Kooi
2017 Jun 13
IGF-1 mediated Neurogenesis Involves a Novel RIT1/Akt/Sox2 Cascade.
Scientific reports
Douglas A. Andres, Ph.D.
2017 Jun 12
Aberrant TGF-β Signaling Drives Castration-Resistant Prostate Cancer in a Male Mouse Model of Prostate Tumorigenesis.
Endocrinology
Natasha Kyprianou, MD
2017 Jun 1
Down syndrome: age-dependence of PiB binding in postmortem frontal cortex across the lifespan.
Neurobiology of aging
H Peter Spielmann
2017 Jun
C/D-box snoRNAs form methylating and non-methylating ribonucleoprotein complexes: Old dogs show new tricks.
BioEssays : news and reviews in molecular, cellular and developmental biology
Stefan Stamm
2017 Jun
Mechanistic insights into energy conservation by flavin-based electron bifurcation.
Nature chemical biology
Anne-Frances Miller
2017 Jun
Quaternary interactions and supercoiling modulate the cooperative DNA binding of AGT.
Nucleic acids research
Michael Gregory Fried
2017 Jul 7
Mechanism-Informed Refinement Reveals Altered Substrate-Binding Mode for Catalytically Competent Nitroreductase.
Structure (London, England : 1993)
Anne-Frances Miller
2017 Jul 5
Mechanism-Informed Refinement Reveals Altered Substrate-Binding Mode for Catalytically Competent Nitroreductase.
Structure (London, England : 1993)
David W Rodgers
2017 Jul 5
Reversion of epithelial-mesenchymal transition by a novel agent DZ-50 via IGF binding protein-3 in prostate cancer cells.
Oncotarget
Natasha Kyprianou, MD
2017 Jul 28
Infiltrating T cells increase IDO1 expression in glioblastoma and contribute to decreased patient survival.
Clinical cancer research : an official journal of the American Association for Cancer Research
Craig Horbinski, M.D., Ph.D.
2017 Jul 27
A Single Outer-Sphere Mutation Stabilizes apo-Mn Superoxide Dismutase by 35 °C and Disfavors Mn Binding.
Biochemistry
Anne-Frances Miller
2017 Jul 25
Immunohistochemical analysis of H3K27me3 demonstrates global reduction in group-A childhood posterior fossa ependymoma and is a powerful predictor of outcome.
Acta neuropathologica
Craig Horbinski, M.D., Ph.D.
2017 Jul 21
Transcription elongation factors represent in vivo cancer dependencies in glioblastoma.
Nature
Craig Horbinski, M.D., Ph.D.
2017 Jul 20
Mutations in the Transmembrane Domain and Cytoplasmic Tail of Hendra Virus Fusion Protein Disrupt Virus-Like-Particle Assembly.
Journal of virology
Rebecca Dutch
2017 Jul 15
Risk factors for the treatment outcome of retreated pulmonary tuberculosis patients in China: an optimized prediction model.
Epidemiology and infection
Craig Horbinski, M.D., Ph.D.
2017 Jul
Inverted Micelle-in-Micelle Configuration in Cationic/Carbohydrate Surfactant Mixtures.
Chemphyschem : a European journal of chemical physics and physical chemistry
Anne-Frances Miller
2017 Jan 4
Synthesis and application of β-carbolines as novel multi-functional anti-Alzheimer's disease agents.
Bioorganic & medicinal chemistry letters
Harry LeVine
2017 Jan 15
Chloroquine-Inducible Par-4 Secretion Is Essential for Tumor Cell Apoptosis and Inhibition of Metastasis.
Cell reports
David S Watt
2017 Jan 10
Bis(N-amidinohydrazones) and N-(amidino)-N'-aryl-bishydrazones: New classes of antibacterial/antifungal agents.
Bioorganic & medicinal chemistry
David S Watt
2017 Jan 1
One-Pot Enzymatic Total Synthesis of Presteffimycinone, an Early Intermediate of the Anthracycline Antibiotic Steffimycin Biosynthesis.
Organic letters
Haining Zhu, Ph.D.
2017 Feb 3
Genome-wide DNA methylation reprogramming in response to inorganic arsenic links inhibition of CTCF binding, DNMT expression and cellular transformation.
Scientific reports
Yvonne N Fondufe-Mittendorf
2017 Feb 2
Adipocytes activate mitochondrial fatty acid oxidation and autophagy to promote tumor growth in colon cancer.
Cell death & disease
Tianyan Gao
2017 Feb 2
Hendra virus fusion protein transmembrane domain contributes to pre-fusion protein stability.
The Journal of biological chemistry
Rebecca Dutch
2017 Feb 17
Dub3 inhibition suppresses breast cancer invasion and metastasis by promoting Snail1 degradation.
Nature communications
Jianhang Jia
2017 Feb 15
SUMO regulates the activity of Smoothened and Costal-2 in Drosophila Hedgehog signaling.
Scientific reports
Jianhang Jia
2017 Feb 14
RIT1 GTPase Regulates Sox2 Transcriptional Activity and Hippocampal Neurogenesis.
The Journal of biological chemistry
Douglas A. Andres, Ph.D.
2017 Feb 10
Epithelial-mesenchymal-transition regulators in prostate cancer: Androgens and beyond.
The Journal of steroid biochemistry and molecular biology
Natasha Kyprianou, MD
2017 Feb
Polyubiquitination of apurinic/apyrimidinic endonuclease 1 by Parkin.
Molecular carcinogenesis
Craig Horbinski, M.D., Ph.D.
2017 Feb