Publications for the month of August 2021

The Department had seven publications listed in PubMed for the month of August 2021.

1: Hammill JT, Sviripa VM, Kril LM, Ortiz D, Fargo CM, Kim HS, Chen Y, Rector J, Rice AL, Domagalska MA, Begley KL, Liu C, Rangnekar VM, Dujardin JC, Watt DS, Landfear SM, Guy RK. Amino-Substituted 3-Aryl- and 3-Heteroarylquinolines as Potential Antileishmanial Agents. J Med Chem. 2021 Aug 26;64(16):12152-12162. doi: 10.1021/acs.jmedchem.1c00813. Epub 2021 Aug 6. PMID: 34355566; PMCID: PMC8404201.

2: Zhang J, Liu Z, Jia J. Mechanisms of Smoothened Regulation in Hedgehog Signaling. Cells. 2021 Aug 20;10(8):2138. doi: 10.3390/cells10082138. PMID: 34440907; PMCID: PMC8391454.

3: Loon A, Zamudio F, Sanneh A, Brown B, Smeltzer S, Brownlow ML, Quadri Z, Peters M, Weeber E, Nash K, Lee DC, Gordon MN, Morgan D, Selenica MB. Accumulation of C-terminal cleaved tau is distinctly associated with cognitive deficits, synaptic plasticity impairment, and neurodegeneration in aged mice. Geroscience. 2021 Aug 19. doi: 10.1007/s11357-021-00408-z. Epub ahead of print. PMID: 34410588.

4: Xie Y, Zhang W, Guo L, Kril LM, Begley KL, Sviripa VM, Chen X, Liu X, Lee EY, He D, Wang C, Gao T, Liu X, Evers BM, Watt DS, Liu C. Potent Synergistic Effect on C-Myc-Driven Colorectal Cancers Using a Novel Indole-Substituted Quinoline with a Plk1 Inhibitor. Mol Cancer Ther. 2021 Aug 10. doi: 10.1158/1535-7163.MCT-20-1017. Epub ahead of print. PMID: 34376582.

5: Mak CA, Weis K, Henao T, Kuchtova A, Chen T, Sharma S, Meekins DA, Thalmann M, Vander Kooi CW, Raththagala M. Cooperative Kinetics of the Glucan Phosphatase Starch Excess4. Biochemistry. 2021 Aug 10;60(31):2425-2435. doi: 10.1021/acs.biochem.1c00307. Epub 2021 Jul 28. PMID: 34319705.

6: Coenen DM, Heinzmann ACA, Oggero S, Albers HJ, Nagy M, Hagué P, Kuijpers MJE, Vanderwinden JM, van der Meer AD, Perretti M, Koenen RR, Cosemans JMEM. Inhibition of Phosphodiesterase 3A by Cilostazol Dampens Proinflammatory Platelet Functions. Cells. 2021 Aug 5;10(8):1998. doi: 10.3390/cells10081998. PMID: 34440764; PMCID: PMC8392606.

7: Zamakhaeva S, Chaton CT, Rush JS, Ajay Castro S, Kenner CW, Yarawsky AE, Herr AB, van Sorge NM, Dorfmueller HC, Frolenkov GI, Korotkov KV, Korotkova N. Modification of cell wall polysaccharide guides cell division in Streptococcus mutans. Nat Chem Biol. 2021 Aug;17(8):878-887. doi: 10.1038/s41589-021-00803-9. Epub 2021 May 27. PMID: 34045745; PMCID: PMC8403489.